Biliary Secretory Failure in Man

Article1 September 1966Biliary Secretory Failure in ManThe Problem of CholestasisSHEILA SHERLOCK, M.D., F.R.C.P., F.R.C.P.E., F.A.C.P. (HON.)SHEILA SHERLOCK, M.D., F.R.C.P., F.R.C.P.E., F.A.C.P. (HON.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-3-397 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe diagnosis of the type and cause of jaundice is usually an easy clinical exercise. The majority of patients will be suffering from hepatocellular jaundice due to acute viral hepatitis or cirrhosis or surgical cholestatic jaundice due to cholelithiasis or carcinoma of the pancreas or liver. Such conditions will be obvious to most junior physicians. There remains a proportion in which difficulty arises, and this is especially so when the distinction between medical and surgical jaundice is required. This paper describes a group of patients in whom surgical jaundice is simulated, although the origin lies within the liver. An anatomical...References1. YAMAMOTOSKANDERBERGZIPURSKYISRAELS TJALG: The early appearing bilirubin: evidence for two components. J. Clin. Invest. 44: 31, 1965. CrossrefMedlineGoogle Scholar2. ROBINSONOWENFLOCKSCHMID SHCAEVR: Bilirubin formation in the liver from nonhemoglobin sources. Experiments with isolated perfused rat liver. Blood 26: 823, 1965. CrossrefMedlineGoogle Scholar3. ELIAS H: Embryology, histology and anatomy of the biliary system, in The Biliary System, edited by TAYLOR, W. Blackwell, Oxford, 1965. Google Scholar4. WHEELER HO: The function of the biliary tract, in Progress in Liver Diseases, edited by POPPER, H., SCHAFFNER, F. Grune & Stratton, New York and London, 1965. CrossrefGoogle Scholar5. RAIA S: Histochemical demonstration of conjugated and unconjugated bilirubin using a modified diazo-reagent. Nature (London) 205: 304, 1965. 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Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByThe Prediction of Hepatotoxiclty Due to Therapeutic Agents in ManHepatic Toxicity of Estrogen in Armenian and Chinese HamstersEstrogen-induced hepatic toxicity and hepatic cancer: differences between two closely related hamster speciesLiver bilirubin UDP-glucuronosyltransferase activity in chronic nonhemolytic unconjugated hyperbilirubinemia of adultsTreatment of acute cholecystitisDiethylstilbestrol-Induced Jaundice in the Chinese and Armenian HamsterChronic intrahepatic cholestasis of sarcoidosisInheritance of the Dubin-Johnson-Sprinz SyndromeBile acid metabolism in infants and children.Benign familial recurrent intrahepatic cholestasisSerum bile acids in primary biliary cirrhosisThe effect of an oral contraceptive on serum lipidsBenign Recurrent Intrahepatic CholestasisAcute nephrotic syndrome as a manifestation of active Hodgkin's diseaseSerum alkaline phosphatase at the onset of Hodgkin's diseasePreoperative Preparation of the Jaundiced Patient: A Review of Current PracticePathophysiology of cholestasisAssessment of Liver Function in Man with Special Reference to HepatotoxicityIntrahepatic Cholestasis Due to AzathioprinePrimary biliary cirrhosisThe Differential Diagnosis of JaundiceOvulatory suppressants, estrogens, and carbohydrate metabolismBILIRUBIN METABOLISM AND JAUNDICE WITH SPECIAL REFERENCE TO UNCONJUGATED HYPERBILIRUBINAEMIAInterference with Bile Pigment Uptake in the Liver by Flavaspidic AcidSevere Postoperative Hyperbilirubinemia Simulating Obstructive JaundiceGenetic Aspects of Liver Disease Associated with Jaundice 1 September 1966Volume 65, Issue 3Page: 397-408KeywordsBiliary systemCholelithiasisCirrhosisExerciseGeneticsHepatitisHepatitis A virusHepatitis E virusLiverPancreas Issue Published: 1 September 1966 CopyrightCopyright ©, 1966, by The American College of PhysiciansPDF DownloadLoading ...