Key result
Electrical injury was associated with a significantly prolonged mean QTc interval compared to healthy controls (412.81 ms vs 396.31 ms; p=0.009).
Why the study?
Novel ECG parameters of ventricular repolarization are related to ventricular arrhythmias, but their status in patients with electrical injuries required investigation.
Do electrical injuries alter ventricular repolarization parameters on ECG compared to healthy controls?
Case-Control (n=71)
Blinded outcome assessment
No
Do electrical injuries alter ventricular repolarization parameters on ECG compared to healthy controls?
Electrical injuries are associated with prolonged QTc intervals, and those with elevated troponin levels show further repolarization abnormalities, suggesting a higher risk for ventricular arrhythmias.
May warrant QTc monitoring for arrhythmia risk post-injury; hypothesis-generating in Level 4 data, needing prospective validation.
Objective: Prolonged T-peak to T-end (Tp-e), a ventricular repolarization parameter, has been related with ventricular arrhythmias (VAs). Novel electrocardiogram (ECG) parameters of ventricular repolarization have received considerable attention recently. In this study, we sought to investigate ventricular repolarization indexes such as the Tp-e and corrected Tp-e (Tp-ec) intervals, Tp-e/QT, Tp-e/QTc, and Tp-ec/QT ratios in patients with electrical injuries (EIs). Methods: Thirty-six patients diagnosed with EIs and 35 age- and sex-matched healthy control patients were included. Admission ECGs of the EI patients were compared with those of the healthy controls. QT and QTc intervals were measured, and the Tp-e and Tp-ec intervals, Tp-e/QT, Tp-ec/QT, and Tp-e/QTc ratios were then calculated from a 12-lead surface ECG. Results: The QT, Tp-e, Tp-e/QT, Tp-e/QTc, Tp-ec/QT were not significantly different between the control group and the EI group (p > 0.05). However, the mean QTc interval was significantly higher in the EI group compared to the control group (412.81 ± 25.46 vs 396.31 ± 26.47 ms; p:0.009). Furthermore, the Tp-ec and Tp-ec/QT of the EI subgroup with elevated troponin levels significantly differed from those of the EI patients with normal troponin levels (p:0.033 and p:0.016, respectively). Conclusions: This retrospective study indicated that patients with EIs tend to have a prolonged QTc interval. Additionally, Tp-ec and Tp-ec/QT, which reportedly designate the tendency for VAs, were significantly higher in the EI patients with elevated troponin I levels than the EI patients with normal troponin levels, suggesting that patients with myocardial injury may be prone to VAs.
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A 2020 study conducted a case-control in Electrical injury (n=71). Electrical injury vs. Healthy controls was evaluated on Mean QTc interval (ms) (p=0.009). Electrical injury was associated with a significantly prolonged mean QTc interval compared to healthy controls (412.81 ms vs 396.31 ms; p=0.009).
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