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The injection replication method was used in a study of the vascular system in cancer of the larynx. Following maceration, clean microcorrosion casts of the blood vessels of larynx cancer were examined in a scanning electron microscope (SEM). The effective filling of the whole vasculature, including its finest capillaries, makes it possible to obtain really three-dimensional pictures of the tumor blood vessels in the SEM. These SEM pictures allow a more detailed and profound analysis of the behavior and arrangement of blood vessels in three basic, angioarchitectonically differentiated zones of the tumor.
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Miodoński et al. (1980) studied this question.
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