Key result
Measurement of platelet adhesiveness by collagen-sepharose and glass bead column methods showed distinct patterns across different congenital and acquired platelet function disorders, proving effective for diagnosis.
Why the study?
Does the collagen/sepharose method provide different diagnostic information for platelet adhesiveness compared to the glass beads column method in various diseases?
Population
170 subjects, including patients with congenital platelet function disorders, acquired disorders, cerebral…
Comparison
Measurement of platelet adhesiveness using… vs Glass beads column method, Baumgartner's method…
Design
Cross-sectional
Follow-up
2-3 months for the aspirin subgroup
Authors
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May complement glass bead testing in platelet disorder evaluation; leaves open prospective validation before diagnostic adoption.
Cross-Sectional (n=170)
Does the collagen/sepharose method provide different diagnostic information for platelet adhesiveness compared to the glass beads column method in various diseases?
The collagen/sepharose method provides complementary diagnostic information to the glass beads method for platelet function disorders, as it is not inhibited by aspirin and shows normal adhesiveness in thrombasthenia.
Kanshi MASE (1986) conducted a cross-sectional in Platelet function abnormalities (n=170). Platelet adhesiveness measurement methods (CS, GBC, Baumgartner's) vs. Healthy controls was evaluated on Platelet adhesiveness. Measurement of platelet adhesiveness by collagen-sepharose and glass bead column methods showed distinct patterns across different congenital and acquired platelet function disorders, proving effective for diagnosis.