Controlling the selectivity of glassy carbon flow detectors using covalently attached monolayers

Significant improvements in selectivity for amperometric detection in flow analysis are achieved at covalently modified glassy carbon electrodes. Flow detectors modified with p‐alkylbenzene (alkyl = methyl, decyl) and p‐phenylacetate monolayers demonstrate how selectivity may be obtained on the basis of solute hydrophobicity and charge. The modified electrodes are stable under hydrodynamic conditions and in aqueous and mixed aqueous/organic carrier streams.