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October 10, 2022BMC Musculoskeletal DisordersOpen Access

Preoperative anemia and deep vein thrombosis in patients with perioperative bone trauma: a cohort study

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Key result

Preoperative anemia significantly increased the risk of perioperative deep vein thrombosis in patients with bone trauma (RR 1.50, 95% CI 1.105-2.036, P=0.009).

Why the study?

The incidence of perioperative lower extremity DVT remains high in bone trauma despite active prevention, and the relationship between preoperative anemia and DVT is unclear.

Does preoperative anemia increase the risk of perioperative deep vein thrombosis in patients with femoral and pelvic fractures?

Population

1049 patients with femoral and pelvic fractures who received surgical treatment

Comparison

Preoperative anemia vs non-anemia

Design

Retrospective propensity score-matched cohort study

Authors

HZHui ZhangChinese PLA General HospitalLWLinqin WuThe Affiliated Yongchuan Hospital of Chongqing Medical UniversityBCBo ChengFirst Affiliated Hospital of Guangzhou Medical University

Discussion

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Member takes

Implication

Preoperative anemia is a significant risk factor for perioperative deep vein thrombosis in patients undergoing surgery for femoral and pelvic fractures.

Study Design

Type

Cohort (n=701)

Multicenter

No

Structured PICO

Does preoperative anemia increase the risk of perioperative deep vein thrombosis in patients with femoral and pelvic fractures?

P
Population
701 adult patients with femoral and pelvic fractures undergoing surgical treatment, retrospectively analyzed to assess the impact of preoperative anemia on perioperative deep vein thrombosis.
E
Exposure
Preoperative anemia
C
Comparator
No preoperative anemia
O
Outcome
Perioperative deep vein thrombosis (DVT)hard clinical

Main Result

Relative Risk: 1.5 (95% CI 1.105–2.036)

Absolute Event Rate: 30.7% vs 20.77%

p-value: p=0.009

Preoperative anemia is a significant risk factor for perioperative deep vein thrombosis in patients undergoing surgery for femoral and pelvic fractures.

Limitations

  • Single-center retrospective study with potential selection bias
  • Different hemoglobin level thresholds based on sex
  • Did not analyze the relationship between the severity of anemia and DVT formation

Cite This Study

Zhang et al. (2022) conducted a cohort in Perioperative bone trauma (femoral and pelvic fractures) (n=701). Preoperative anemia vs. Non-anemic was evaluated on Perioperative deep vein thrombosis (DVT) (RR 1.500, 95% CI 1.105-2.036, p=0.009). Preoperative anemia significantly increased the risk of perioperative deep vein thrombosis in patients with bone trauma (RR 1.50, 95% CI 1.105-2.036, P=0.009).

synapsesocial.com/papers/6a96acb3d45ba51c86b2e871https://doi.org/10.1186/s12891-022-05869-7
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