Key result
Injection of coliform organisms from polio patients, their toxins, and virulent poliomyelitis virus into Macacus rhesus monkeys accelerated the production of poliomyelitis.
Population
Macacus rhesus monkeys
Design
Preclinical
Authors
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May suggest bacterial co-factors accelerate poliomyelitis in primates; leaves open human relevance or therapeutic implications.
The study demonstrates that combining coliform organisms and their toxins with virulent poliomyelitis virus accelerates the production of poliomyelitis in a monkey model.
Toomey et al. (1949) studied Poliomyelitis. Coliform organisms, their toxins, and virulent poliomyelitis virus was evaluated on Accelerated production of poliomyelitis. Injection of coliform organisms from polio patients, their toxins, and virulent poliomyelitis virus into Macacus rhesus monkeys accelerated the production of poliomyelitis.
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