Carbohydrate–lectin recognition plays important roles in cell–cell communication, proliferation, and differentiation. We report here a new approach of using a carbohydrate-encapsulated gold nanoparticle (shown in purple) as an affinity probe for the efficient separation and enrichment of target proteins, and then protein identification and epitope mapping by MALDI-TOF MS.
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Chen et al. (2005) studied this question.
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