Key result
Female sex (3-fold higher risk, P<0.001), larger initial aneurysm diameter, current smoking, and higher mean blood pressure were independently associated with an increased risk of aneurysm rupture.
Why the study?
What baseline risk factors are associated with aneurysm rupture in patients with small abdominal aortic aneurysms?
Cohort (n=2,257)
What baseline risk factors are associated with aneurysm rupture in patients with small abdominal aortic aneurysms?
Effect estimate: 3-fold higher risk (for female sex)
p-value: p=<0.001
Female sex, larger initial aneurysm diameter, current smoking, and higher mean blood pressure are independent risk factors for the rupture of small abdominal aortic aneurysms.
Authors
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May support intensified surveillance in women and smokers with small AAAs; hypothesis-generating for risk-factor modification pending prospective validation.
Powell et al. (2001) conducted a cohort in Small abdominal aortic aneurysms (n=2,257). Female sex, larger aneurysm diameter, smoking, and higher blood pressure was evaluated on Aneurysm rupture (3-fold higher risk (for female sex), p=<0.001). Female sex (3-fold higher risk, P<0.001), larger initial aneurysm diameter, current smoking, and higher mean blood pressure were independently associated with an increased risk of aneurysm rupture.
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