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March 24, 1997FEBS Letters

Glutamine‐330 is not essential for activity in isopenicillin N synthase from Aspergillus nidulans

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Authors

MSMalkit SamiImmunocore (United Kingdom)TBToby J. N. BrownPRPeter L. RoachUniversity of Southampton

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Sami et al. (1997) studied this question.

synapsesocial.com/papers/6a96ddd6a64ccd99870e2a83https://doi.org/10.1016/s0014-5793(97)00176-2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Dioxygen Activation by Enzymes with Mononuclear Non-Heme Iron Active Sites1996 · 728 citations
  2. 2Isopenicillin N synthase: mechanistic studies1990 · 248 citations
  3. 3Cloning and expression in Escherichia coli of isopenicillin N synthetase genes from Streptomyces lipmanii and Aspergillus nidulans1988 · 141 citations
  4. 4Functional Analysis of Conserved Histidine Residues in Cephalosporium acremonium Isopenicillin N Synthase by Site-directed Mutagenesis1996 · 43 citations
  5. 5Ferrous Active Site of Isopenicillin N Synthase: Genetic and Sequence Analysis of the Endogenous Ligands1996 · 66 citations