Effect of phacoemulsification on corneal endothelium in type 1 and type 2 diabetes mellitus

PurposeThe aim of this study is to compare the effect of phacoemulsification oncornealendothelium in type 1 and 2 of diabetes mellitus (DM).Patients and methodsThis study is a retrospective, interventional, comparative study that included400eyes of 320 patients with DM and with visually significant cataract. Thepatientswere divided into two equal groups: one group with type 1 and theother with type 2DM. Specular microscopy assessing the endothelial cellcount was done beforesurgery and after it 1 and 3 months in both groups.ResultsThe two groups were highly comparable to each other regarding the meanage,axial length, manifest refraction, and endothelial cell count.Postoperatively, therewas a statistically significant difference between thetwo groups regarding theendothelial cell count. Both groups hadendothelial cell loss from mean of2150–1879 in type 1 DM group and from2213 to1995 in type 2 DMgroup. Theendothelial cell loss was more in type1 DM group than in type 2DM (P<0.005).ConclusionPhacoemulsification produces endothelial cell loss in diabetic patients more intype1 than in type 2 DM.