Key result
Combined intra-arterial BUdR infusion and megavoltage irradiation achieved local control in all 3 children with unresectable osteogenic sarcomas.
Why the study?
Does combined intra-arterial BUdR infusion and megavoltage irradiation provide local control in children with unresectable osteogenic sarcomas?
Population
3 children with osteogenic sarcomas which were either unresectable or whose parents refused permission to…
Design
Case_series
Follow-up
1 to 2 years
Authors
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Does not support practice change for unresectable pediatric osteosarcoma; leaves open efficacy of combined BUdR-irradiation.
Case Report (n=3)
Does combined intra-arterial BUdR infusion and megavoltage irradiation provide local control in children with unresectable osteogenic sarcomas?
Combined intra-arterial BUdR infusion and megavoltage irradiation achieved local control in a small series of children with unresectable osteogenic sarcomas.
Goffinet et al. (1975) conducted a case report in Osteogenic sarcomas (n=3). Combined intra-arterial 5'bromodeoxyuridine (BUdR) infusion and high-dose-per-fraction megavoltage irradiation was evaluated on Local control. Combined intra-arterial BUdR infusion and megavoltage irradiation achieved local control in all 3 children with unresectable osteogenic sarcomas.
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