We present a case of cystic fibrosis (CF) diagnosed at the age of 79, one of the oldest CF cases known to date.Our patient had an unconventional CF genotype, leading to an odyssey of a clinical journey that involved frequent treatment modifications and advanced genetic testing.The course was complicated by multiple prolonged recurrent hospitalizations, requiring extensive geriatrics, and pulmonary multidisciplinary collaborative care.This case illustrates the complexity of caring for geriatric patients with CF, highlighting the following key geriatrics M's: (m)ulti-complexity, (m) obility, (m)edications, and what (m)atters most.
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Lee et al. (2025) studied this question.
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