Key result
Mitral valve replacement in a 2-year-old girl with dilated cardiomyopathy and severe mitral regurgitation led to significant clinical improvement and weight gain over 3 years of follow-up.
Why the study?
Dilated cardiomyopathy is characterized by left ventricular dilation and dysfunction, and its association with significant mitral regurgitation worsens prognosis.
Does mitral valve replacement improve clinical status in a 2-year-old child with dilated cardiomyopathy and severe mitral regurgitation?
Case Report (n=1)
No
Does mitral valve replacement improve clinical status in a 2-year-old child with dilated cardiomyopathy and severe mitral regurgitation?
Mitral valve replacement may be a feasible option to improve clinical status and delay the need for heart transplantation in selected children with dilated cardiomyopathy and severe mitral regurgitation.
BACKGROUND: Dilated cardiomyopathy (DCM) is characterized by left ventricular dilation and dysfunction. The association with significant mitral regurgitation worsens the prognosis. CASE REPORT: A 2-year-old girl presented with DCM and severe mitral regurgitation. She had a history of viral myocarditis at the age of 4 months, necessitating recurrent hospital admissions for management of intractable heart failure, pneumonia, and failure to thrive. The decision was taken to proceed for mitral valve surgery, which ended with mitral valve replacement. Over 3 years of follow-up after surgery, there was significant improvement in her weight gain and she improved clinically. There were still recurrent admissions, but mostly for adjustment of her deranged anticoagulation medications. CONCLUSION: Mitral valve surgery might be indicated in selected patients with DCM.
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Mashali et al. (2020) conducted a case report in Dilated cardiomyopathy with severe mitral regurgitation (n=1). Mitral valve replacement was evaluated on Clinical improvement and weight gain. Mitral valve replacement in a 2-year-old girl with dilated cardiomyopathy and severe mitral regurgitation led to significant clinical improvement and weight gain over 3 years of follow-up.
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