Seven patients who applied corticosteroids topically under occlusive dressings acquired severe first-degree burns after exposure to sunlight. The response was unusual because normal skin, occluded but not treated with steroid creams, was more severely burned than the diseased areas. Skin-testing with artificial light showed the causative factor to be the modality (occlusion) rather than the medicine (steroids).
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Andrew N. Cattano (1970) studied this question.
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