Neutron diffraction study reveals stable glucose hydration and minimal water network disruption across concentrations, suggesting glucose does not alter bulk water structure.
Neutron diffraction experiments were carried out at ambient temperature on aqueous solutions of glucose at concentrations of 1, 3, and 5 molal. The difference methods of neutron diffraction and isotopic substitution were used to determine various structure factors associated with all the exchangeable hydrogen atoms of the solutions. The results imply that the hydration of the glucose molecule is not concentration sensitive. It is also found that the average water structure itself is relatively unperturbed by the presence of glucose.
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Mason et al. (2003) studied this question.
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