As a part of studies on nonnarcotic antipyretic-analgesic, 1-(2-tert-aminoalkyl)-3, 4-dihydrocarbostyril (III : R'=H), 1-(2-tert-aminoalkyl)-6-hydroxy-3, 4-dihydrocarbostyril (III : R'=6-OH), and 1-(2-tert-aminoalkyl)-7-hydroxy-3, 4-dihydrocarbostyril (III : R'=7-OH) were synthesized. Analgesic, antitussive, and antipyretic action of these compounds were examined and some of these compounds showed anticipated activity.
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Noboru Shigematsu (1961) studied this question.
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