⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

January 1, 2004HeterocyclesOpen Access

Synthesis of (-)-Tuliparin B Utilizing 2-Bromo-1-alkenes Conveniently Synthesized from the 3-O-Substituted 1,2-Dibromoalkane System by Regioselective Elimination

Shigeru Nishiyama Tadaaki Ohgiya

View Full Paper

Ask AI

Bookmark

Share

Ask about this paper

Answers are grounded in this paper and cite their sources.

Ask your own question…

Abstract

Synthesis of (-)-tulipalin B with a variety of biological properties including cutaneous allergenic activity, was accomplished by using the 2-bromo-1-alkenes synthesized by the regioselective HBr elimination reaction of 3acyloxy-1,2-dibromoalkanes.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Nishiyama et al. (2004) studied this question.

synapsesocial.com/papers/6a970d85d73097a25cb2dbec https://doi.org/10.3987/com-04-10183

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Occupational allergic contact dermatitis caused by decorative plantsOriginal Research · 1996 · 54 citations
2Allergenic .alpha.-methylene-.gamma.-butyrolactones. Study of the capacity of .beta.-acetoxy- and .beta.-hydroxy-.alpha.-methylene-.gamma.-butyrolactones to induce allergic contact dermatitis in guinea pigsOriginal Research · 1986 · 25 citations
3Use of enzymic hydrolysis of dimethyl malates for a short synthesis of tulipalin B and of its enantiomerOriginal Research · 1985 · 41 citations
4The Asymmetric Baylis−Hillman ReactionOriginal Research · 1997 · 195 citations
5COMBINATION OF BORANE-DIMETHYL SULFIDE COMPLEX WITH CATALYTIC SODIUM TETRAHYDROBORATE AS A SELECTIVE REDUCING AGENT FOR α-HYDROXY ESTERS. VERSATILE CHIRAL BUILDING BLOCK FROM (S)-(−)-MALIC ACIDOriginal Research · 1984 · 161 citations

Total Synthesis of (+)-Blastmycinone, (−)-Litsenolide C1, and Related Natural Trisubstituted Lactones via Alkynyltungsten Compounds2000
Vinylalumination for the Synthesis of Functionalized Allyl Alcohols, Vinylepoxides, and α-Alkylidene-β-hydroxy-γ-lactones2003
Conversion of 3-O-Substituted 1,2-Dibromoalkanes into 2-Bromo-1-alkenes by the Selective Elimination: Its Application to Total Synthesis of 12-Oxygenated Tremetones2004
Hydroxychloroquine: Chemistry and Medicinal ApplicationsHeterocycles · 2023
An Efficient Route for the Synthesis of 2-Arylbenzothiazoles in an Ionic Liquid, Using Ultrasound IrradiationHeterocycles · 2023

More from Heterocycles

More from Keio University