Prediction of β‐turns

A residue‐coupled model is proposed to predict the β‐turns in proteins. The rates of correct prediction for the 455 β‐turn tetrapeptides and 3807 non‐β‐turn tetrapeptides in the training database are 94.7 and 81.3%, respectively. The rates of correct prediction for the 110 β‐turn tetrapeptides and 30229 non‐β‐turn tetrapeptides in the testing database are 80.0 and 80.2%, respectively. Compared with the rates of correct prediction based on the residue‐independent model reported previously, the quality of prediction is significantly improved by the new model, implying that the residue‐coupled effect along a polypeptide chain is important for the formation of reversal turns, such as β‐turns, during the process of protein folding.