Two siblings with the rare phenotype Rhnull are described; the parents are related to each other. Serologic investigation of the family gives indirect support for the action of an amorphous gene. As demonstrated in the propositus, the splenectomy resulted in health improvement. Titration tests in 1,803 unrelated blood donors revealed 4 heterozygous — types. On the basis of this calculation one can assume one Rhnull patient among 6 million inhabitants.
No takes yet. Share an insight, caveat, or question.
Seidl et al. (1972) studied this question.