A False-Positive Lupus Erythematosus Test

Case Reports1 May 1955A FALSE-POSITIVE LUPUS ERYTHEMATOSUS TESTA. GERSON JACOBS, M.D.A. GERSON JACOBS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-42-5-1097 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFollowing the description of Hargraves, Richmond and Morton1in 1948 of peculiar cells among the blood elements of patients with disseminated lupus erythematosus, there have been numerous studies of the specificity of that cell (called L.E. cell). Although the majority of the studies relate the L.E. cell to disseminated lupus erythematosus, there have been reports of the finding of these cells in other disease entities. Many of these reports of "false-positive" L.E. cells are not detailed studies, and none records postmortem findings. This paper concerns the finding of markedly positive L.E. cell preparations in a patient with widespread tuberculosis but...Bibliography1. HargravesRichmondMorton MMHR: Presentation of 2 bone marrow elements: "tart" cell and "L.E." cell, Proc. Staff Meet., Mayo Clin. 23: 25-28, 1948. MedlineGoogle Scholar2. ZimmerHargraves FEMM: The effect of blood coagulation on L.E. cell formation, Proc. Staff Meet., Mayo Clin. 27: 424-431, 1952. MedlineGoogle Scholar3. BermanAxelrodGoodmanMcLaughry LARHLRI: So-called "lupus erythematosus inclusion phenomenon" of bone marrow and blood; morphologic and serologic studies, Am. J. Clin. Path. 20: 403-418, 1950. CrossrefMedlineGoogle Scholar4. LeeMichaelVural SLSRIL: L.E. (lupus erythematosus) cell: clinical and chemical studies, Am. J. Med. 10: 446-451, 1951. CrossrefMedlineGoogle Scholar5. Hargraves MM, cited as a personal communication by Montgomery, H., and McCreight, W. G.: Disseminated lupus erythematosus, Arch. Dermat. and Syph. 60: 356-372, 1949. 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FinchRossEbaugh SCJFFG: Immunologic mechanisms of leucocyte abnormalities, J. Lab. and Clin. Med. 42: 555-569, 1953. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Brooklyn, N. Y.*Received for publication October 22, 1954.From the Department of Medical Services, Maimonides Hospital of Brooklyn, Brooklyn, N. Y.†Present address: 8000 High School Road, Elkins Park, Pennsylvania. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMedikamentös induzierter systemischer Lupus erythematodesDrug-induced systemic lupus erythematosus: A critical reviewCurrent status of the LE cell testDer viscerale Lupus erythematodesTETRACYCLINE PROVOCATION IN LUPUS ERYTHEMATOSUS*CASIMIR A. DOMZ, M.D., F.A.C.P., DELBERT H. MCNAMARA, M.D., F.A.C.P., HANS F. HOLZAPFEL, M.D.RHEUMATISM AND ARTHRITIS: REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (TWELFTH RHEUMATISM REVIEW)* Part IICHARLEY J. SMYTH, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., WILLIAM S. CLARK, M.D., F.A.C.P., DARRELL C. CRAIN, M.D., F.A.C.P., FELIX E. DEMARTINI, M.D., IVAN F. DUFF, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P. (C), MAX M. MONTGOMERY, M.D., F.A.C.P., BERNARD M. NORCROSS, M.D., F.A.C.P., HOWARD F. POLLEY, MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P.The L. E. phenomenon and systemic lupus erythematosusPLEURITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS: ITS IMPORTANCE AS AN EARLY MANIFESTATION IN DIAGNOSIS*WILLIAM A. WINSLOW, M.D., LESTER N. PLOSS, M.D., BERNARD LOITMAN, M.D.The incidence of the L.E. cell phenomenon in patients with rheumatoid arthritis. (A two-year study)Rheumatoid Arthritis and Systemic Lupus ErythematosusTHE L. E. PHENOMENON IN RHEUMATOID ARTHRITIS*IRVING A. FRIEDMAN, M.D., JEROME F. SICKLEY, M.D., ROBERT M. POSKE, M.D., ARNOLD BLACK, M.D., DAVID BRONSKY, M.D., WILSON H. HARTZ JR., M.D., CHARLOTTE FELDHAKE, B.S., PAUL S. REEDER, M.D., ELI M. KATZ, M.D.Immunohämatologie der Thrombocyten und Leukocyten 1 May 1955Volume 42, Issue 5Page: 1097-1100KeywordsBlood cellsCellsLupus erythematosusMedical servicesMetastasisSpecificity Issue Published: 1 May 1955 PDF downloadLoading ...