Key result
Tibial bone vasculature demonstrates active vasoconstriction in response to sympathoexcitatory stimuli, which is smaller, delayed, and more variable compared with whole leg vasculature.
Why the study?
Noninvasive, in vivo investigation of human bone blood perfusion control on a moment-by-moment basis had not yet been performed.
Does sympathoexcitatory stimuli induce active vasoconstriction in tibial bone vasculature in young healthy individuals?
Observational
Does sympathoexcitatory stimuli induce active vasoconstriction in tibial bone vasculature in young healthy individuals?
This study provides the first in vivo evidence that human tibial bone vasculature actively vasoconstricts in response to sympathetic stimulation.
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First in vivo evidence of sympathetic vasoconstriction in human tibial bone vessels; leaves open its role in bone perfusion and disease.
Draghici et al. (2020) conducted an observational in Healthy. Sympathoexcitatory stimuli vs. Whole leg vasculature was evaluated on Vasoconstrictor response. Tibial bone vasculature demonstrates active vasoconstriction in response to sympathoexcitatory stimuli, which is smaller, delayed, and more variable compared with whole leg vasculature.
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