Catalytic Asymmetric CC Bond Formation: New Enolato‐ and Organolithium Chemistry

Catalytic and enantioselective are two new efficient processes for CC bond formation developed from fundamental reactions of organolithium compounds. Koga et al. have achieved the benzylation of Li enolates in the presence of both chiral (L*) and achiral (L) ligands [Eq.(a)], and Denmark et al. describe the addition of RLi to aryl imines [Eq. (b)] with very good selectivities, R  Me, vinyl.