Carbene‐Catalyzed Three‐Component Cascade Reaction of Benzofuran‐2‐ones and Enals: Construction of Spirobenzofuranone‐δ‐lactones

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A convenient method was developed via an NHC mediated three‐component cascade reaction for the construction of medicinally important spirobenzofuranone derivatives. The reaction features mild reaction conditions and generates three consecutive stereocenters, one of which is an all‐carbon substitution. The protocol can accommodate various substituents and substitution patterns, afford the products in moderate to good yields with excellent diastereoselectivities and moderate enantioselectivity.