Iminium ions generated upon amide activation were trapped sequentially with tethered nucleophiles. This cascade of cyclizations constitutes a new synthetic strategy that was applied to the construction of the tricyclic core of alkaloid securinol B.
No takes yet. Share an insight, caveat, or question.
Larouche‐Gauthier et al. (2008) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: