All articles of this category When a γ-hydroxyallene (various β-allenylcarbinols or 4,5-hexadienoic acid) is allowed to react with aryl or alkenyl halides in the presence of (Ph 3 P) 4 Pd and base, cyclization and coupling to form the title compounds in 14 - 78 (average 50)% yields occurs. A mechanism in which an aryl- or alkenylpalladium(II) halide initiates the cyclization by intramolecular oxypalladation is discussed.
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Walkup et al. (1993) studied this question.