Answers are grounded in this paper and cite their sources.
The concise total synthesis of marine alkaloids, (-)-flustramines A and B, and (-)-flustramides A and B has been achieved through the domino olefination/isomerization/Claisen rearrangement (OIC) for highly enantioselective construction of the asymmetric quaternary carbon center and the chemoselective reduction-cyclization (RC) for pyrrolidine formation as key steps.
No takes yet. Share an insight, caveat, or question.
Kawasaki et al. (2005) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: