Key result
The paper describes the chemical synthesis of cis and trans isomers of an isoxazoline ring-hydroxylated metabolite of roxifiban, a platelet glycoprotein IIb/IIIa receptor antagonist.
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Synthetic metabolite standards now available for study; leaves open any clinical relevance to roxifiban use.
Batt et al. (2000) studied this question. The paper describes the chemical synthesis of cis and trans isomers of an isoxazoline ring-hydroxylated metabolite of roxifiban, a platelet glycoprotein IIb/IIIa receptor antagonist.
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