Highly Efficient and Practical Optical Resolution of 2-Amino-2′-hydroxy-1,1′-binaphthyl by Molecular Complexation withN-Benzylcinchonidium Chloride: A Direct Transformation to Binaphthyl Amino Phosphine

A new type of N,P chiral ligand (1) was synthesized through a simple and practical resolution of racemic 2-amino-2′-hydroxy-1,1′-binaphthyl (2) by molecular complexation in the solid state. The procedure represents the first example of the optical resolution of an amino alcohol with a chiral ammonium salt.