Key result
Prostaglandin E1 (10^-8 to 10^-7 molar) effectively improves the preparation of human platelet concentrates from platelet-rich plasma and whole blood.
Population
Human plasma rich in platelets and whole blood (in vitro)
Design
Preclinical
Authors
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May warrant further in vitro optimization of platelet concentrates; leaves open clinical transfusion benefits pending human trials.
Prostaglandin E1 improves the in vitro preparation of human platelet concentrates, suggesting potential utility for blood banks.
Shio et al. (1972) studied this question. Prostaglandin E1 (10^-8 to 10^-7 molar) effectively improves the preparation of human platelet concentrates from platelet-rich plasma and whole blood.
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