Enantioselective intramolecular cycloaddition of hexaynes with 1,3‐diyne moiety was examined. Chiral Rh catalyst provided axially chiral 1,1′ ‐bis(biphenylenyl) derivatives by consecutive [2+2+2] cycloaddition. In contrast, chiral Ir catalyst provided axially chiral macrocyclic compounds with 1,3‐diyne moiety by single [2+2+2] cycloaddition.
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Shibata et al. (2011) studied this question.
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