Key result
Total arch replacement with the frozen elephant trunk technique significantly increased the rate of complete false lumen thrombosis at the bronchial carina compared to total arch replacement alone (100% vs 25%, p<0.0001).
Why the study?
Does the frozen elephant trunk (FET) technique improve downstream aortic remodeling and reduce the need for additional surgeries compared to traditional total arch replacement in patients with Stanford type A aortic dissection?
Cohort (n=50)
No
Does the frozen elephant trunk (FET) technique improve downstream aortic remodeling and reduce the need for additional surgeries compared to traditional total arch replacement in patients with Stanford type A aortic dissection?
Absolute Event Rate: 100% vs 25%
p-value: p=<0.0001
The frozen elephant trunk technique during total arch replacement for Stanford type A aortic dissection significantly improves distal aortic remodeling and reduces the need for subsequent downstream aortic interventions compared to traditional total arch replacement.
FET may promote distal remodeling in type A dissection; leaves open whether RCTs confirm fewer reinterventions.
The frozen elephant trunk (FET) technique allows single-stage extended surgical repair of Stanford type A aortic dissection and has shown promotion of aortic remodeling by maintaining the true lumen flow and facilitating its expansion and by promoting false lumen thrombosis. However, few studies have compared the effectiveness of FET technique, in terms of the downstream aortic remodeling. Between 2005 and 2017, 50 patients underwent total arch replacement for Stanford type A aortic dissection, including that with (n = 22) and without FET technique (n = 28). We compared distal aortic remodeling in patients who underwent total arch replacement with (using a J-Graft open stent graft) or without the technique. The false lumen complete thrombosis rate and the ratio of true lumen area at three levels of the descending aorta were evaluated post operation. In FET group, the diameter and length of the stent graft were 29.0 ± 3.9 mm and 70.9 ± 17.4 mm, respectively. The in-hospital death with and without the FET technique was 0 and 3, respectively, with no late death in both groups. Eight patients (28.6%) only in the non-FET group required additional surgical treatment for downstream aorta. In the FET group, the ratio of true lumen area at the level of bronchial carina and false lumen complete thrombosis rate at the levels of bronchial carina and aortic valve were significantly higher than non-FET group. A more favorable remodeling in the descending aorta was observed in patients who underwent FET associated with a total arch replacement compared to those who underwent total arch replacement alone.
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Tochii et al. (2018) conducted a cohort in Stanford type A aortic dissection (n=50). Frozen elephant trunk (FET) technique using J-Graft open stent graft vs. Total arch replacement without FET was evaluated on False lumen complete thrombosis at the level of bronchial carina (p=<0.0001). Total arch replacement with the frozen elephant trunk technique significantly increased the rate of complete false lumen thrombosis at the bronchial carina compared to total arch replacement alone (100% vs 25%, p<0.0001).
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