Key result
Compared to 31 normal subjects, 33 patients with coronary slow flow phenomenon had significantly increased levels of osmolarity, tonicity, sodium, glucose, BUN, haematocrit, and haemoglobin.
Why the study?
Are indicators of dehydration and haemoconcentration associated with the coronary slow flow phenomenon?
Case-Control (n=64)
Are indicators of dehydration and haemoconcentration associated with the coronary slow flow phenomenon?
Markers of haemoconcentration and dehydration are significantly associated with the coronary slow flow phenomenon, suggesting a potential pathophysiological role.
Dehydration markers were associated with coronary slow flow; hypothesis-generating and requires prospective validation before any clinical consideration.
Objectives: The coronary slow flow phenomenon (CSFP), characterized by decreased distal progression of dye to coronary arteries, is a distinct angiographic phenomenon and little is known about its pathophysiology. Although several hypotheses have been suggested, the underlying mechanism of CSFP has not been well established yet. The aim of this study was to determine the roles of indicators of dehydration and haemoconcentration in CSFP which have blood flow abnormality effects. Methods: The study consisted of 33 patients with CSFP (group 1), and 31 normal subjects as control group (group 2) detected by coronary angiography. CSFP was diagnosed by the TIMI frame count method. Serum electrolytes, osmolarity and haematological parameters were measured. Results: Compared with control subjects, patient with CSFP had increased levels of calculated osmolarity, tonicity, sodium, glucose and blood urea nitrogen (BUN). Significant differences were also observed in the haematocrit, haemoglobin concentration, and calculated osmolarity but not in total cholesterol and albumin. Conclusions: The results of the present study indicate that the markers of haemoconcentration and dehydration are significantly associated with CSFP. The markers may be important in the coronary blood flow anomaly.
No takes yet. Share an insight, caveat, or question.
Kargın et al. (2010) conducted a case-control in Coronary slow flow phenomenon (n=64). Indicators of dehydration and haemoconcentration vs. Normal subjects was evaluated on Levels of serum electrolytes, osmolarity, and haematological parameters. Compared to 31 normal subjects, 33 patients with coronary slow flow phenomenon had significantly increased levels of osmolarity, tonicity, sodium, glucose, BUN, haematocrit, and haemoglobin.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: