Key result
A 40-year-old man with untreated hypertension and erythrocytosis developed recurrent deep vein thrombosis and hypoxemia following COVID-19 pneumonia, consistent with Gaisbock syndrome.
Case Report (n=1)
This case highlights the potential for Gaisbock syndrome to present with recurrent deep vein thrombosis following COVID-19 pneumonia in a patient with pre-existing hypertension and erythrocytosis.
Alerts clinicians to Gaisbock syndrome in hypertensive erythrocytosis with post-COVID thrombosis; leaves open causal links for prospective study.
In 1905, Felix Gaisbock, MD, described a syndrome in patients with hypertension, elevated hematocrit levels, plethoric appearances, and no splenomegaly. He postulated this relative erythrocytosis was due to stress. In this case report, a 40-year-old Caucasian man with obesity was admitted with recurrent deep vein thrombosis and increasing oxygen requirements 2 weeks after hospitalization with COVID-19 pneumonia. This patient had a 10-year history of untreated hypertension and erythrocytosis. He had a ruddy appearance, a normal erythropoietin level, and a negative JAK2 V617 mutation. In this case, Gaisbock syndrome was suspected.
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Evans et al. (2022) conducted a case report in Gaisbock syndrome, COVID-19 pneumonia, deep vein thrombosis (n=1). COVID-19 pneumonia was evaluated. A 40-year-old man with untreated hypertension and erythrocytosis developed recurrent deep vein thrombosis and hypoxemia following COVID-19 pneumonia, consistent with Gaisbock syndrome.
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