Enantioselective Synthesis of Unsymmetrical Triarylmethanes by Chiral Brønsted Acids

Chiral Brønsted acid catalyzed Friedel–Crafts alkylation of electron‐rich arenes with (3‐indolyl)methanamines has been realized to provide an efficient synthesis of enantioenriched unsymmetrical triarylmethanes. With 5 mol‐% of a newly developed chiral phosphoric acid, the enantioenriched unsymmetrical triarylmethanes were obtained in excellent yields with up to 91 % ee.