Sepsis in pediatric burn patients

OBJECTIVE: To review the specific infections common in pediatric burns, including their categorization, diagnosis, and treatment. DESIGN: Review of the literature and expert opinion. RESULTS: Children with serious burns are prone to a host of septic complications. This proclivity to infection is secondary to the immunosuppressive effect of burn injury, the loss of the skin and mucosal physical barriers, and the requirement for invasive support devices. CONCLUSION: Sepsis is common in the pediatric burn patient and can markedly increase morbidity and mortality. Anticipation, prompt diagnosis of infection, and effective therapy can result in successful outcomes for many of these children.