Non small cell lung cancer with targetable driver alterations: Imaging perspective

This is the authors' abstract. We don't add key points for this paper.

The discovery of targetable driver alterations has transformed the treatment paradigm in advanced non-small cell lung cancer (NSCLC). Small molecule tyrosine kinase inhibitors have increased survival in the treatment of metastatic NSCLC, and it is now standard of care to screen for targetable driver mutations. The knowledge of imaging findings that are characteristic of specific driver alterations will help to identify, triage, and initiate early treatment in patients. This review will explore the most common driver alterations in NSCLC, the recent advances in targeted therapy, and the characteristic clinical and imaging features.