Key result
Endomyocardial biopsy was successfully performed in 82% of 18 children, providing positive morphological diagnoses in 3 cases and actively helpful findings in 7 other cases.
Why the study?
Is endomyocardial biopsy safe and diagnostically useful in children?
Observational (n=18)
Is endomyocardial biopsy safe and diagnostically useful in children?
Endomyocardial biopsy is a safe procedure in children that provides useful diagnostic information in a significant proportion of cases.
May support biopsy consideration in select pediatric cases; leaves open confirmation of safety and utility in larger prospective studies.
Endomyocardial biopsy was attempted in 18 children aged 5 months to 15 years with 82% success. Biopsies obtained from 15 children were examined by light and electron microscope making positive morphological diagnoses in 3 cases. The biopsy findings were actively helpful in 7 other cases, which contrasts with experience in adult biopsy series. This is a low risk procedure which does not add to the hazards of cardiac catheterization in children.
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Mackay et al. (1977) reported an observational. Endomyocardial biopsy was evaluated on Procedural success. Endomyocardial biopsy was successfully performed in 82% of 18 children, providing positive morphological diagnoses in 3 cases and actively helpful findings in 7 other cases.
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