Why the study?
Timely diagnosis of perforative duodenal ulcer can be difficult and contradictory, especially in patients presenting in the acute period of ischemic stroke with high risks of both thromboembolism and bleeding.
Case Report (n=1)
In a patient with acute ischemic stroke and a perforated duodenal ulcer, early postoperative anticoagulation with unfractionated heparin was safely managed despite high bleeding and thromboembolic risks.
Supports feasibility of early UFH after ulcer repair in acute stroke; hypothesis-generating and requires prospective confirmation.
Perforated duodenal ulcer is a common pathology with fairly high postoperative mortality, especially in late diagnosis. In some cases, timely diagnosis of a perforative ulcer may be difficult and the results of the survey may be contradictory. The classical triad of clinical signs of perforative ulcers is not always observed in patients, sometimes the clinical picture is so unclear that the final diagnosis can only be made intraoperative. The article presents an analysis of the clinical case of difficult diagnosis and treatment of perforative duodenal ulcer in a patient in an acute period of ischemic stroke. In addition, the patient had severe concomitant somatic pathology with a high risk of systemic thromboembolism and at the same time a high risk of bleeding.
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Abramov et al. (2023) conducted a case report in Perforated duodenal ulcer and acute ischemic stroke (n=1). Surgical repair and early anticoagulation with unfractionated heparin was evaluated on Clinical recovery without hemorrhagic or thromboembolic complications.
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