Anionic Host Molecules with Bicyclic Carbon Skeletons—Synthesis and Guest Inclusion in Aqueous Solution

The inclusion of neutral, organic guest molecules, e.g., benzene, in host compounds in aqueous solution has been achieved with the new cavity compound 1, RCONa⊕, and the analogue with CCH3 instead of the two central benzene rings. The 1H-NMR signals of entrapped benzene molecules are strongly shifted to high field.