Key result
Balloon angioplasty successfully relieved native discrete coarctation of the aorta in 92.5% of patients, significantly reducing the peak systolic pressure gradient from 51.97 mmHg to 9.075 mmHg immediately post-procedure.
Cohort (n=40)
No
Absolute Event Rate: 9.075% vs 51.97%
p-value: p=<0.001
Balloon angioplasty is an effective short-term treatment for discrete aortic coarctation in children and infants, significantly reducing pressure gradients and allowing most patients to discontinue antihypertensive medications, though recoarctation remains a risk.
May support immediate relief in pediatric coarctation; leaves open durability versus surgery in prospective trials.
Introduction: Balloon angioplasty has been proposed as an alternative way to surgery in primary treatment of aortic coarctation (Co A) for both children and infants.
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A 2017 study conducted a cohort in Native discrete coarctation of the aorta (n=40). Balloon angioplasty vs. Pre-intervention baseline was evaluated on Peak to peak systolic pressure gradient (mmHg) (p=<0.001). Balloon angioplasty successfully relieved native discrete coarctation of the aorta in 92.5% of patients, significantly reducing the peak systolic pressure gradient from 51.97 mmHg to 9.075 mmHg immediately post-procedure.
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