On the Distribution of Cadmium in Blood

Cadmium in the blood has been considered to be bound to haemoglobin. In the blood of mice given repeated injections of CdCl2 (0.5 mg Cd/kg), however, more than 60 per cent of the cadmium was bound to a protein substance with low molecular weight (about 10,000), clearly separable from haemoglobin by G‐75 Sephadex chromatography. In other mice given repeated injections of 0.25 mg Cd/kg, about 25 per cent of blood‐cadmium was associated with this substance.