A new perfusate (solution C3) was applied to the hypothermic preservation of human cadaveric kidneys before transplantation, with excellent results. Twelve of the kidneys so preserved with storage times up to 9 hours 27 minutes manifested immediate adequate function, avoiding the need for post-transplant dialysis. Two kidneys stored for longer than 12 hours suffered acute tubular necrosis, as did four others in which buffered Hartmann's solution was used as the perfusate.
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Collins et al. (1971) studied this question.
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