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Piroxicam (20 mg o.d.), ibuprofen (200 mg t.i.d.) or placebo were added to the conventional treatment in three different groups of professional athletes with soft-tissue injuries. The piroxicam-treated group showed, with a once-a-day only administration, a statistically significant better improvement of various subjective and objective signs of functional damage.
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Santilli et al. (1980) studied this question.
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