In Saccharomyces cerevisiae , ammonia can be incorporated into the amino group of glutamate, the source of 80% of cellular nitrogen, by two pathways: the reductive amination of 2-ketoglutarate, catalyzed by glutamate dehydrogenase, in which NADPH serves as the source of electrons, or by the ATP-
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Boris Magasanik (2003) studied this question.
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