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The macrocyclic trichothecene triester 3′‐hydroxy‐2′‐deoxy‐2",3",4",5"‐tetrahydroverrucarin A (37), has been synthesized starting from the sesquiterpene alcohol verrucarol (3), adipic acid and a derivative of mevalonic acid (14). The latter has been prepared from 4‐(tetrahydro‐2‐pyranyloxy)‐2‐butanone (9).
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Notegen et al. (1981) studied this question.
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