Stimulation of the snail's tentacle nerves results in hyperpolarization and inhibition of the 'giant serotonin-containing neurone'located in the brain. Glutamic acid mimics this effect. Available data indicate that the reversal potential for the glutamic acid effect is very similar to that of the synaptic action being about 5 to 8 mV more negative than the resting potential in each case.
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Cottrell et al. (1972) studied this question.
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