Key result
Beta blockers showed the effect to reduce exacerbations and exacerbation-related mortality in patients with COPD in some cases.
Why the study?
Chronic obstructive pulmonary disease is the third leading cause of mortality worldwide, prompting a review of the association between beta blocker use and COPD mortality.
Does beta blocker use reduce mortality in patients with COPD?
Systematic Review
Does beta blocker use reduce mortality in patients with COPD?
This systematic review suggests that beta blocker use may reduce exacerbations and exacerbation-related mortality in patients with COPD, though further studies are needed.
Beta blockers may reduce COPD exacerbations and related mortality; leaves open need for confirmatory RCTs on overall survival.
Background: Chronic obstructive pulmonary disease (COPD) it is currently the third greatest cause of mortality worldwide and one of the main causes of morbidity Aims: This systematic review is to review the association of beta blocker use and COPD mortality. Methods: This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. Result: In the PubMed database, the results of our search brought up 249 articles, whereas the results of our search on SCIENCE DIRECT brought up 18.876 articles, our search on SAGEPUB brought up 4.844 articles. The results of the search conducted for the last year of 2014 yielded a total 131 articles for PubMed, 6.875 articles for SCIENCE DIRECT and 1.840 articles for SAGEPUB. In the end, we compiled a total of 8 papers, 5 of which came from PubMed, 2 of which came from SCIENCE DIRECT and 1 of which came from SAGEPUB. We included eight research that met the criteria. Conclusion: In summary, beta blockers showed the effect to reduce the exacerbation or exacerbation related mortality of COPD in some cases. More studies needed in the future for more evidence of the use of beta blockers as the treatments in patients with COPD.
No takes yet. Share an insight, caveat, or question.
Irawan et al. (2024) conducted a systematic review in Chronic Obstructive Pulmonary Disease (COPD). Beta blockers vs. Placebo or no beta blocker was evaluated on COPD mortality and exacerbations. Beta blockers showed the effect to reduce exacerbations and exacerbation-related mortality in patients with COPD in some cases.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: