Key result
The historical development and pharmacological mechanisms of antiplatelet drugs, including aspirin, thienopyridines, and GPIIb/IIIa antagonists, have established their role in preventing arterial thrombosis.
This paper provides a comprehensive historical perspective on the discovery and development of antiplatelet therapies, highlighting the critical role of optical aggregometry.
Affirms established antiplatelet therapies for arterial thrombosis prevention; extends historical context to inform next-generation drug research.
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Gustav V. R. Born (2006) conducted a review in Arterial thrombosis. Antiplatelet drugs was evaluated. The historical development and pharmacological mechanisms of antiplatelet drugs, including aspirin, thienopyridines, and GPIIb/IIIa antagonists, have established their role in preventing arterial thrombosis.
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