Key result
In critically ill patients admitted to the ICU for non-cardiac reasons, admission NT-proBNP was independently associated with the need for renal replacement therapy (adjusted OR 1.40 per doubling of NT-proBNP).
Why the study?
Are admission levels of cTnT, cTnI, and NT-proBNP associated with maximum stage of AKI and need for acute RRT in critically ill patients admitted to the ICU for non-cardiac reasons?
Population
138 adult patients admitted to the intensive care unit (ICU) for non-cardiac reasons
Design
Cohort
Authors
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NT-proBNP on ICU admission may aid AKI risk stratification in non-cardiac patients; leaves open prospective validation and intervention trials.
Observational (n=138)
No
Are admission levels of cTnT, cTnI, and NT-proBNP associated with maximum stage of AKI and need for acute RRT in critically ill patients admitted to the ICU for non-cardiac reasons?
Odds Ratio: 1.4 (95% CI 1.09–1.81)
p-value: p=0.008
In critically ill patients admitted for non-cardiac reasons, admission NT-proBNP is independently associated with the maximum stage of AKI and the need for renal replacement therapy.
Haines et al. (2017) conducted an observational in Acute kidney injury in critically ill patients (n=138). NT-proBNP vs. Lower levels of NT-proBNP was evaluated on Maximum stage of AKI and need for acute renal replacement therapy (Stage 3 AKI with RRT vs lower stage) (OR 1.40, 95% CI 1.09-1.81, p=0.008). In critically ill patients admitted to the ICU for non-cardiac reasons, admission NT-proBNP was independently associated with the need for renal replacement therapy (adjusted OR 1.40 per doubling of NT-proBNP).